Update on Male Hormonal Contraception: Is the Vasectomy in Jeopardy?

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Advances in male hormonal contraception

Contraception is a basic human right for its role on health, quality of life and wellbeing of the woman and of the society as a whole. Since the introduction of female hormonal contraception the responsibility of family planning has always been with women. Currently there are only a few contraceptive methods available for men, but recently, men have become more interested in supporting their pa...

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Clinical trials in male hormonal contraception.

Research has established the principle of hormonal male contraception based on suppression of gonadotropins and spermatogenesis. All hormonal male contraceptives use testosterone, but only in East Asian men can testosterone alone suppress spermatogenesis to a level compatible with contraceptive protection. In Caucasians, additional agents are required of which progestins are favored. Clinical t...

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Male Hormonal Contraception: Where Are We Now?

Hormonal male contraception clinical trials began in the 1970s. The method is based on the use of exogenous testosterone alone or in combination with a progestin to suppress the endogenous production of testosterone and spermatogenesis. Studies using testosterone alone showed that the method was very effective with few adverse effects. Addition of a progestin increases the rate and extent of su...

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Vasectomy and other vasal occlusion techniques for male contraception

METHODS — The only effective method available for male contraception is vasectomy, which divides the vas deferens in a minor surgical procedure [1]. The procedure takes about 15 minutes and can be performed in an appropriately equipped office or ambulatory surgery center [2]. No-scalpel vasectomy is the preferred vasectomy technique in the United States (US) because of its lower complication ra...

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Rising to the challenge of male hormonal contraception

More than a quarter of couples worldwide depend on male contraception.1 Yet, vasectomy aside, male contraceptives are not very reliable. The unintended pregnancy rate with condoms, for example, is 15% to 20% a year.2 This unreliability probably helps explain why more than half of men might try a male hormonal contraceptive (MHC).3 Indeed, new male contraceptives seem to be popular across all ra...

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ژورنال

عنوان ژورنال: International Journal of Impotence Research

سال: 2010

ISSN: 0955-9930,1476-5489

DOI: 10.1038/ijir.2010.2